Wu Min2020-01-09T16:14:04+08:00

WU Min

Collaborator, Mechanobiology Institute, National University of Singapore

dbswum@nus.edu.sg
+65 6601 2310
CBIS Blk S1A, Level 2 Lee Wee Kheng Bldg
National University of Singapore
14 Science Drive 4
Singapore 117557

Laboratory website
Wu Lab Deconstructing the Endocytic Machinery

Research Program
The Cell-Matrix and Cell-Cell Mechanotransduction Group

Affiliations
Department of Biological Sciences, National University of Singapore

Recent Research

Wu Min

Collaborator

Research Areas

Endocytosis, Membrane traffic, Curvature, Actin cytoskeleton, Mechanotransduction

Research Interests

Dr Wu is interested in elucidating the principles underlying the organization and dynamics of the subcellular membrane compartments. Specifically her lab investigates how biological membranes are shaped through collective protein-lipid interactions and how geometry of the membrane compartment is coupled to cellular functions. The Wu Lab uses a combination of cell biological, biophysical and biochemical approaches to address these questions.

Biography

Dr Wu Min graduated from Peking University in China and received her bachelor degree in Chemistry. She did her graduate studies at Cornell University with Dr Barbara Baird, where she initiated the use of patterned lipid bilayers as antigen-presenting platforms and studied immune cell activation and signal transduction. During her post-doctoral research in the laboratory of Dr Pietro De Camilli at Yale School of Medicine, she focused on the molecular mechanisms of endocytosis. In 2011, she was awarded the NRF fellowship, joining CBIS/MBI in the fall.

Education

PhD Cornell University

Recent Publications

  1. Chen Y, Yong J, Martínez-Sánchez A, Yang Y, Wu Y, De Camilli P, Fernández-Busnadiego R, and Wu M. Dynamic instability of clathrin assembly provides proofreading control for endocytosis. J. Cell Biol. 2019;. [PMID: 31451612]
  2. . https://www.ncbi.nlm.nih.gov/pubmed/31390543
  3. Yong J, Chen Y, and Wu M. Real-Time Monitoring of Clathrin Assembly Kinetics in a Reconstituted System. Methods Mol. Biol. 2018; 1847:177-187. [PMID: 30129017]
  4. Yang Y, and Wu M. Rhythmicity and waves in the cortex of single cells. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 2018; 373(1747). [PMID: 29632268]
  5. McPherson PS, and Wu M. Light, space, and time in cancer signaling. Mol. Biol. Cell 2018; 29(6):688. [PMID: 29535172]
  6. Wu Z, Su M, Tong C, Wu M, and Liu J. Membrane shape-mediated wave propagation of cortical protein dynamics. Nat Commun 2018; 9(1):136. [PMID: 29321558]
  7. Yang Y, Xiong D, Pipathsouk A, Weiner OD, and Wu M. Clathrin Assembly Defines the Onset and Geometry of Cortical Patterning. Dev. Cell 2017; 43(4):507-521.e4. [PMID: 29161594]
  8. Xiao S, Tong C, Yang Y, and Wu M. Mitotic Cortical Waves Predict Future Division Sites by Encoding Positional and Size Information. Dev. Cell 2017; 43(4):493-506.e3. [PMID: 29161593]
  9. Wu M. Pulses and waves of contractility. J. Cell Biol. 2017;. [PMID: 29138250]
  10. Ang Z, Xiong D, Wu M, and Ding JL. FFAR2-FFAR3 receptor heteromerization modulates short-chain fatty acid sensing. FASEB J. 2017;. [PMID: 28883043]

Lab Members

About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.