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MBInsights Annual

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MBI Science Communications 


An annual summary of research at the Mechanobiology Institute, National University of Singapore

The purpose of these synopses is to show the breadth of the research coming from the MBI. We are very proud of the fact that we have been able to build an institute with state-of-the-art capabilities in super-resolution microscopy and microfabrication. Our open lab environment and the energy of our students and postdocs have combined to take advantage of our experimental tools to answer important biological questions. Because we believe that these tools should be utilized to solve many more problems in the biomedical sciences, we invite you and your colleagues to join us in collaborative studies to solve those problems. Many different disciplines are needed since the problems need the tools of physicists, biologists, computational scientists, and engineers, working side-by-side to better understand how biological systems integrate mechanical cues and physical forces from the world around them.

We hope that you find these research summaries interesting, and we invite you to join us in collaborative studies at the MBI.

MBInsights Annual 2016

The cover depicts the formation of the actin rim around the nucleus in response to a distant force, which may act as a shield to protect DNA from mechanical forces and stabilize nuclear functions. For more details, please read the feature “Forces Acting Far and Wide” on pages 14-15.

Read the MBInsights Annual, 2016 Edition

MBInsights Annual 2017

The cover reimagines the classic image of a Nautilus shell from On Growth and Form. Here, the chambers of the shell have been replaced by cells undergoing processes commonly studied in mechanobiology, e.g. extrusion, phagocytosis, apoptosis, blebbing, and contraction. For more details, please read the feature “100 years of On Growth and Form” on pages 30-33.

Read the MBInsights Annual, 2017 Edition