Image by the Kanchanawong Lab

The 3rd International Symposium on Mechanobiology (ISMB 2017) concluded on 14th December, 2017.

Read a full report about the symposium

The 3rd International Symposium on Mechanobiology (ISMB 2017) will cover fundamentals, recent advances and emerging issues, providing a unique opportunity to advance knowledge and understanding in mechanobiology.

The 3rd International Symposium on Mechanobiology (ISMB 2017) is organized by the Mechanobiology  Institute, National University of Singapore and the International Society of Mechanobiology. This symposium is the third in a series of scientific meetings supported and endorsed by the International Society of Mechanobiology, the first two being held in Shanghai and Okayama respectively.

The symposium aims to cover the fundamentals, recent advances and emerging issues related to mechanobiology. It will provide a unique opportunity to advance knowledge and understanding in the areas of basic and applied research in mechanobiology.

This field involves interdisciplinary approaches combining biology with mechanics/physics as well as experimental techniques and computational modelling.

In addition, mechanobiology has also increasingly been involved in the study of a plethora of biological and pathological processes, including development, aging, infection as well as diseases such as cancer. A wide spectrum of these aspects across multiscales from the molecular, cellular, tissue to the organ level will be covered in this symposium.

We look forward to welcoming you in Singapore in 2017.

Download complete abstract book and programme (registrants only, password required)

Topics to include

  • Molecular biomechanics

  • Cellular mechanics

  • Nuclear mechanics

  • Tissue mechanics

  • Organ mechanics

  • Cytoskeletal dynamics

  • Mechanosensitive channels

  • Mechanosensing and mechanosignaling

  • Cell Migration

  • Matrix assembly and remodeling

  • Adhesion site assembly and dynamics

  • Mechanobiology of Diseases

  • Bacterial-host interactions and pathogenesis

  • Skin mechanobiology

  • Mechanomedicine

  • Nano/Microfabrication

  • Nano/Microfluidics

  • Tools & Techniques in mechanobiology

  • Microscopy

  • Computational and theoretical modeling

  • Bio- and biomimetic materials

  • Tissue engineering and regenerative medicine

  • Synthetic biology

  • Immuno-mechanobiology



The organizers are honored to welcome the following speakers to present at the 3rd International Symposium on Mechanobiology (ISMB 2017).

Plenary Speakers

Anna Akhmanova

Ulrecht University, Netherlands

The Akhmanova group studies cytoskeletal organization and trafficking processes, which contribute to cell polarization, differentiation, vertebrate development and human disease. They are interested in understanding, at a systems level, how different aspects of cell architecture are coordinated.The main focus of their studies is the microtubule cytoskeleton. Learn more.

Benny Geiger

Weizmann Institute of Science, Israel

Benny Geiger’s Lab focuses in particular on integrin- and cadherin-mediated adhesions, studying the mechanisms whereby they sense external surfaces, and recognizing not only their chemical composition, but also their physical properties, including their topography, rigidity and ligand density. Learn more.

Birgit Lane

IMB-A star, Singapore

Current projects in Birgit Lane’s Lab include mechanical signaling in keratinocyte wound activation; therapeutic strategies for keratin disorders; susceptibilities to non-melanoma skin cancer; post-translational regulation of keratin filament proteins; and genetic mechanisms underlying skin disorders. The lab has also established a renowned knowledgebase, the Human Intermediate Filament Database. Learn more.

Thomas Lecuit

Aix-Marseille University, France

Thomas Lecuit’s Tissue Architecture and Plasticity Lab studies how epithelial tissues maintain a robust organisation and extensively remodel as they grow and change their shape during development. Their findings are leading to a general framework of morphogenesis based on spatial control over cell deformation by actomyosin flows and stabilization, and temporal control by contractile pulses. Learn more.

Satyajit Mayor

National Centre for Biological Sciences, India

Satyajit Mayor’s Mechanisms of Membrane Organization and Endocytosis Lab explores the fine structure of the plasma membrane, providing for the first time an in vivo picture of lipidic assemblies. Their work provides a new understanding of how membrane rafts may be created and an understanding of the role of specialized endocytic mechanisms for the establishment of developmental gradients and the regulation of membrane tension. Learn more.

Beth L Pruitt

Stanford University, USA

Pruitt’s lab seeks to understand the role of mechanics in biology and force sensitive pathways in cell-cell adhesion and subcellular organization, the role of mechanical environment on the structure and function of stem cell derived cardiomyocytes as biophysical models of health and disease, and to develop models of mechanical signaling underlying the sense of touch and hearing. Learn more.

Michael Sheetz

Mechanobiology Institute, National University of Singapore

The morphology of cells, organs and whole organisms is determined by the generation of forces on the immediate environment, which is either extracellular matrix or adjacent cells. The Sheetz Lab is engaged in studies to understand the detailed molecular mechanisms involved in a variety of phenomena from cancer metastasis to brain function. Learn more.

Masatoshi Takeichi

RIKEN Centre for Developmental Biology, Japan

The Takeichi Lab is researching the mechanisms involved in the formation of tissues from cells from the perspective of cell-cell adhesion and cytoskeleton organization. Their research will contribute to the understanding of not only basic mechanisms of animal morphogenesis but also of pathological cell behavior, such as cancer invasion and metastasis. Learn more.

Keynote Speakers

Alexander Bershadsky

Mechanobiology Institute, Singapore

Bianxiao Cui

Stanford University, USA

Delphine Delacour

Institut Jacques Monod, France

Kristian Franze

University of Cambridge, UK

Ben Goult

University of Kent, UK

Peter Gunning

University of New South Wales, Australia

Linda Kenney

Mechanobiology Institute, Singapore

Boris Martinac

Victor Chang Cardiac Research Institute, Australia

Kenji Matsuno

Osaka University, Japan

Toshihiko Ogura

Tohoku University, Japan

Tom Perkins

University of Colorado, Boulder, USA

Jacques Prost

Institut Curie, France

Vivek Shenoy

University of Pennsylvania, USA

Chunguang Wang

Tonji University, China

Rebecca Wells

University of Pennsylvania, USA

Alpha Yap

University of Queensland, Australia

Keynote Speakers
(Special Sessions)