About the National University of Singapore

About NUSA leading global university centred in Asia, NUS is Singapore's flagship university, offering a global approach to education and research with a focus on Asian perspectives and expertise.

About the Mechanobiology Institute, National University of Singapore

About MBIOne of four Research Centres of Excellence at NUS, MBI is working to identify, measure and describe how the forces for motility and morphogenesis are expressed at the molecular, cellular and tissue level.
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News and Featured Events

Upcoming events, conferences, outreach and more at MBI.

2016 MBI-BPS Thematic Meeting on the Mechanobiology of Disease

Recent meeting brings together scientists to discuss research on the physical basis of disease

By | Oct 9th, 2016|Categories: Conference and Workshops, News|Comments Off on 2016 MBI-BPS Thematic Meeting on the Mechanobiology of Disease

Awards and Honors

MBI acknowledges our celebrated principal investigators and researchers.

Visiting Scientists

Collaborators and Visiting Scientists

Visiting faculty, on-site guests and visitors.

MBI Publications

Latest Publications

  1. Zhang Z, Xia S, and Kanchanawong P. An integrated enhancement and reconstruction strategy for the quantitative extraction of actin stress fibers from fluorescence micrographs. BMC Bioinformatics 2017; 18(1):268. [PMID: 28532442]
  2. Radhakrishnan AV, Jokhun DS, Venkatachalapathy S, and Shivashankar GV. Nuclear Positioning and Its Translational Dynamics Are Regulated by Cell Geometry. Biophys. J. 2017; 112(9):1920-1928. [PMID: 28494962]
  3. Jagielska A, Lowe AL, Makhija E, Wroblewska L, Guck J, Franklin RJM, Shivashankar GV, and Van Vliet KJ. Mechanical Strain Promotes Oligodendrocyte Differentiation by Global Changes of Gene Expression. Front Cell Neurosci 2017; 11:93. [PMID: 28473753]
  4. Mitra A, Venkatachalapathy S, Ratna P, Wang Y, Jokhun DS, and Shivashankar GV. Cell geometry dictates TNFα-induced genome response. Proc. Natl. Acad. Sci. U.S.A. 2017;. [PMID: 28461498]
  5. Saxena M, Liu S, Yang B, Hajal C, Changede R, Hu J, Wolfenson H, Hone J, and Sheetz MP. EGFR and HER2 activate rigidity sensing only on rigid matrices. Nat Mater 2017;. [PMID: 28459445]
  6. Li BL, Setyawati MI, Chen L, Xie J, Ariga K, Lim C, Garaj S, and Leong DT. Directing Assembly and Disassembly of 2D MoS2 Nanosheets with DNA for Drug Delivery. ACS Appl Mater Interfaces 2017;. [PMID: 28452468]
  7. Saw TB, Doostmohammadi A, Nier V, Kocgozlu L, Thampi S, Toyama Y, Marcq P, Lim CT, Yeomans JM, and Ladoux B. Topological defects in epithelia govern cell death and extrusion. Nature 2017; 544(7649):212-216. [PMID: 28406198]
  8. Ding WY, Ong HT, Hara Y, Wongsantichon J, Toyama Y, Robinson RC, Nédélec F, and Zaidel-Bar R. Plastin increases cortical connectivity to facilitate robust polarization and timely cytokinesis. J. Cell Biol. 2017;. [PMID: 28400443]
  9. Yuan G, Le S, Yao M, Qian H, Zhou X, Yan J, and Chen H. Elasticity of the Transition State Leading to an Unexpected Mechanical Stabilization of Titin Immunoglobulin Domains. Angew. Chem. Int. Ed. Engl. 2017;. [PMID: 28394039]
  10. Kukumberg M, Yao JY, Neo DJH, and Yim EKF. Microlens topography combined with vascular endothelial growth factor induces endothelial differentiation of human mesenchymal stem cells into vasculogenic progenitors. Biomaterials 2017; 131:68-85. [PMID: 28380401]

All MBI publications

Recent Publication Articles